D Louvel, M Delvaux, A Felez, J Fioramonti, L Bueno, Y Lazorthes, J Frexinos Laboratory of Digestive Motility, Gastroenterology Unit, CHU Rangueil, Toulouse, France. AIM: The effects of oxytocin on colonic perception of intraluminal distension were evaluated in 26 patients with irritable bowel syndrome (IBS), using a flaccid bag placed in the descending colon and connected to a computerised barostat. METHOD: Symptomatic responses (first sensation and pain) were evaluated during isobaric distensions (4 mm Hg increments, five minute duration, five minute interval with return to zero pressure between each step),......... Read more at: http://gut.bmj.com/cgi/content/abstract/39/5/741